Phase II Effect Size (Signal) 0.5
Phase III Target Sample Size 800
Environmental Noise (Variance) 3
Expected Dropout Rate 15%
Probability of Success (PoS)
--%
Simulated outcome distribution

See what BRAKES would do for your trial

Send us your draft protocol and we'll run a full simulation, custom-configured to your endpoints, population, and design.

BRAKES controls the one-sided Type I error rate at 2.5%. Patent pending. ISO 27001:2022 accredited.
Validated across 1M+ simulation runs and live trial data. 0.2% error rate, 6× fewer errors than conventional methods.